Should I use 1 mL or 2 mL of water?

Either works. MOTS-C is a big dose, so with 2 mL a 5 mg dose is a full 100 unit syringe. With 1 mL it is only 50 units, so you inject half as much liquid. The amount of peptide is exactly the same. Most people pick 1 mL for the smaller injection.

Morning. Some people find it stimulating.

Do I need to train for it to matter?

Research pairs it with exercise. Movement is part of the protocol.

Cellular & Longevity

MOTS-C

Mitochondria, energy, and insulin sensitivity

Quick answer

A 10 mg vial with 1 mL of water makes 10 mg/mL. A 5 mg dose is 50 units, half a syringe. Two or three times a week for 4 to 8 weeks.

Mix it: 10 mg vial + 1 mL water
Draw: About 50 units on a U-100 syringe
How often: 2 to 3 times a week
Store it: Refrigerate after mixing. Use within about 4 weeks.

What it is

MOTS-C comes from mitochondrial DNA. Research looks at how cells use energy, how muscle responds to exercise, and how the body handles blood sugar.

Most used for

Exercise capacity
Insulin sensitivity
Metabolic health markers
Age-related energy decline

These are things researchers study. They are not promised results.

Dosing at a glance

These are the amounts used most often in research. Always start at the low end.

Vial size: 10 mg
Dose range: 5 mg to 10 mg per dose in common use. No human study has set a dose.
How often: 2 to 3 times a week
Cycle length: 4 to 8 weeks
Mix with: Bacteriostatic water (also called bac water or reconstitution solution).
Storage: Refrigerate after mixing. Use within about 4 weeks.

Mixing it

A common setup for MOTS-C is a 10 mg vial with 1 mL of bac water.

That makes 10 mg per mL. A 5 mg dose is about 50 units on a standard insulin syringe.

Bacteriostatic water is all you need here. Acetic acid is only for powders that will not dissolve. See the mixing guide.

Open the peptide reconstitution calculator