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Metabolic

GLP-3 RT (Retatrutide)

Three-pathway metabolic research compound

Quick answer

A 10 mg vial with 2 mL of water makes 5 mg/mL. A 1 mg dose is 20 units. Once a week, stepped up every 4 weeks.

Mix it
10 mg vial + 2 mL water
Draw
About 20 units on a U-100 syringe
How often
Once a week, same day each week
Store it
Refrigerate after mixing. Use within about 4 weeks.

What it is

Retatrutide acts on three pathways: GLP-1, GIP, and glucagon. The third pathway is linked to energy burn, which is what separates it from tirzepatide in research.

Most used for

  • Body weight
  • Appetite control
  • Liver fat
  • Metabolic rate

These are things researchers study. They are not promised results.

Dosing at a glance

These are the amounts used most often in research. Always start at the low end.

Vial size
10 mg to 30 mg
Dose range
1 mg to 12 mg per week, increased slowly
How often
Once a week, same day each week
Cycle length
Long term, dose stepped up every 4 weeks
Mix with
Bacteriostatic water (also called bac water or reconstitution solution).
Storage
Refrigerate after mixing. Use within about 4 weeks.

Mixing it

A common setup for GLP-3 RT is a 10 mg vial with 2 mL of bac water.

That makes 5 mg per mL. A 1 mg dose is about 20 units on a standard insulin syringe.

Bacteriostatic water is all you need here. Acetic acid is only for powders that will not dissolve. See the mixing guide.

Open the peptide reconstitution calculator